Xu Zou

KP.3.2.4+Orf3a:K66N, Orf9b:P3L (55 seqs, 8 countries)

6

KP.2.3 has a mutation on Orf3a:67 which is close to this Orf3a:66. It also appears simutaneously in multiple GBW samples from different countries, so make an issue. KP.3.2.4+A10558T+C29218T+A25590T(Orf3a:K66N)+C28291T(Orf9b:P3L) GISAID query:...

KP.2.3+S:G72R,Orf8:S54L(17 seqs, 8 countries)

3

KP.2.3+C28714T+C2434T, G17325A,G21776A,C28054T(S:G72R,Orf8:S54L) GISAID query: C28714T, G21776A, C28054T No. of seqs: 6(Ireland 1 Canada 1 USA 1 Spain 1 UK 2) First: EPI_ISL_19211045,Canada, 2024-6-4 Latest: EPI_ISL_19229011, UK, 2024-6-21 [usher](https://nextstrain.org/fetch/genome-test.gi.ucsc.edu/trash/ct/subtreeAuspice87_genome_test_3e518_5dbe40.json?label=id:node_5467076) 

KP.3.1+Orf1a:A537S,M1769T,S:R237M(29 seqs, 5 countries)

1

KP.3.1+G1874T,C18570T(Orf1a:A537S)+C10450T+T5571C(Orf1a:M1769T)+G22272T(S:R237M) GISAID query: G22272T, T5571C, C10450T No. of seqs: 15(Canada 3 UK 3 France 3 Ireland 1 USA 5) First: EPI_ISL_19157205, France, 2024-5-3 Latest: EPI_ISL_19242590, USA, 2024-6-26 [usher](https://nextstrain.org/fetch/genome-test.gi.ucsc.edu/trash/ct/subtreeAuspice49_genome_test_220b_a24570.json?gt=S.237M&label=id:node_5455877) 

KP.3.3+S:R765L(106 seqs, 9 countries)

8

Previously only in Japan, now spreads to other countries. KP.3.3+G23856T(S:R765L) GISAID query: G23856T, C28291A, G28884C No. of seqs: 25( Japan 23 South Korea 1 Ireland 1) First: EPI_ISL_19146127, 2024-4-15, Japan...

KP.2.3+S:146K(16 seqs, 3 countries)

2

This branch shares the C9298T with JN.1.50, there seems to be many of such homoplastic synonymous mutations now, unsure why. Combined with the KP.2.3-defining C22000A, this is also a 2-nuc...

KP.2.3+S:Q173R (40 seqs, 14 countries)

4

KP.2.3+S:S31del+A22080G(S:Q173R) GISAID query: C22000A, A22080G,G25593T No. of seqs: 20(Canada 2 UK 2 Germany 1 Iceland 1 Ireland 1 Netherlands 3 Singapore 1 Switzerland 1 USA 8(2 from Greece)) First: EPI_ISL_19183126,...

KP.1.1.1+S:T572I,Orf7a:R78L (41 seqs,2 countries, 36 with S:I100L)

3

KP.1.1.1+C27143T+C23277T, G27626T(S:T572I, Orf7a:R78L) GISAID query: C27143T, C23277T, G27626T GISAID query for S:I100L branch: C23277T, G27626T, A21860T First: EPI_ISL_19122349, 2024-4-12, USA Latest: EPI_ISL_19269319, 2024-7-2, USA [usher](https://nextstrain.org/fetch/genome-test.gi.ucsc.edu/trash/ct/subtreeAuspice85_genome_test_357b1_9d4360.json?label=id:node_6256967) 

KS.1+Orf1a:G112S,N470T+S:T22N (29 seqs, 8 countries)

2

There seems to be a new S:T22N -Glycan branch under KS.1 besides KS.1.1 KS.1+A1674C(Orf1a:N470T)+G599A,C5806T(Orf1a:G112S)+C7271T+C21627A(S:T22N) GISAID query: C21627A, A1674C, G599A No. of seq: 10(Canada 1 UK 2 USA 6(3 from France,...

KP.3.5+C1420T+C5512T, T21723C GISAID query:T21723C, C23039G,T22200A No. of seqs: 17(USA 16 Canada 1 ) First: EPI_ISL_19264146, 2024-5-28, USA Latest: EPI_ISL_19329884, 2024-8-1, Canada [usher](https://nextstrain.org/fetch/genome-test.gi.ucsc.edu/trash/ct/subtreeAuspice153_genome_test_2d28e_e91c20.json?label=id:node_5476316) 

This I934V also becomes convergent. KP.1.1.1+C2340T, T9511C, A24362G(Orf1a:S692F,S:I934V) GISAID query: C2340T, T9511C, A24362G GISAID query for S:S680F branch: C2340T, T9511C, A24362G,C23601T No. of seqs: 20(Belgium 1 Finland 1 France 1...