Xu Zou

Results 152 issues of Xu Zou

It seems that there's another KS.1.1/KP.3 recombinant result in the XEC spike of S:T22N,F59S,F456L,Q493E,V1104L. It has a slightly different breakpoint that allows it to keep an additional S:R346T. KS.1.1--KP.3 Breakpoint...

recombinant
Rapid review needed
S:22
S:1104
S:59
FLiRT
FLuQE

KP.2.3+del21653_21655(S:S31del)+C28714T+C18555T+C9298T+C22329T(S:S256L) GISAID query: C22329T, C9298T, C18555T No. of seqs: 23(USA 22(1 from Burkina Faso) China 1(from USA)) First: EPI_ISL_19293728, 2024-6-27, USA-TX Latest: EPI_ISL_19419455, 2024-8-26, USA-TX [usher](https://nextstrain.org/fetch/genome-test.gi.ucsc.edu/trash/ct/subtreeAuspice5_genome_test_41115_e6d120.json?label=id:node_5568746) ![image](https://github.com/user-attachments/assets/952c7379-2b95-4ad6-a727-30180d84d39b)

Emerged in an undersampled area
S:256
S:1104
S:146
DeFLiRT

KP.2.3+del21653_21655(S:S31-)+C28714T+C18555T+G14622A+G23587C(S:Q675H) GISAID query: G23587C, C18555T, G14622A, C28714T No.of seqs: 18(Canada 1 Costa Rica 8 Netherlands 1 USA 8(4 from Nicaragua)) First: EPI_ISL_19254607, USA from Nicaragua, 2024-6-24 Latest: EPI_ISL_19408331, Canada, 2024-8-25...

Emerged in an undersampled area
High local prevalence
Apparently slow
S:675
KP.2.3

This branch floats out of waters when the double node bug is fixed KP.3.1.1+A22116G(S:N185S) GISAID query: A22116G, C12616T, A13121T No. of seqs: 24(Austria 1 Canada 7 Israel 9 UK 7)...

S:185
KP.3.1.1

LP.1.2+C3885A(Orf1a:P1207H)+A22896C(S:H445P) GISAID query: C3885A, T22896C, G22132T No. of seqs: 7(USA 6 Denmark 1) First: EPI_ISL_19289456, USA-FL, 2024-7-3 Latest: EPI_ISL_19350321, USA-GA, 2024-8-12 [usher](https://nextstrain.org/fetch/genome-test.gi.ucsc.edu/trash/ct/subtreeAuspice3_genome_test_59cf8_ff5d50.json?label=id:node_5540713) ![image](https://github.com/user-attachments/assets/5770d90b-f7c0-4eac-aa0e-849a5733bbe4)

Apparently slow
S:445
S:190
DeFLiRT
KP.1.1

XDY+C29466T(N:A398V)+G25166C(S:E1202Q) GISAID query: C29466T,G25166C,G19669A No. of seqs: 15(USA 14(NJ,ND,CT,IA,RI,TX,MN,AZ,NY,NE) Canada 1) First: EPI_ISL_19285227, USA-NY, 2024-7-8 Latest: EPI_ISL_19445747, USA-NJ, 2024-9-10 [usher](https://nextstrain.org/fetch/genome-test.gi.ucsc.edu/trash/ct/subtreeAuspice40_genome_test_9a3d_a0aff0.json?label=id:node_5787850) ![image](https://github.com/user-attachments/assets/15ead42b-6380-4f0d-bc18-395a36da708c)

S:1202
XDY

MB.1.1.1+T16794C+C12896T, G22093T, C22591T, G29398A(Orf1a:P4211S,S:M177I) GISAID query: G22093T, T16794C,C936T No. of seqs: 2(USA from Nicaragua and Austria) EPI_ISL_19445554, GBW from Nicaragua, 2024-9-16 EPI_ISL_19445463, GBW from Austria, 2024-9-18 [usher](https://nextstrain.org/fetch/genome-test.gi.ucsc.edu/trash/ct/subtreeAuspice115_genome_test_990f_a0aed0.json?label=id:node_5414360) ![image](https://github.com/user-attachments/assets/5d235024-a7ec-4d53-a24e-a96cca93580f)

Emerged in an undersampled area
S:177
MB.1.1

It seems another KP.3.1.1+S:R346T branch is emerging KP.3.1.1+A29716T+G22599C(S:R346T) GISAID query: A29716T, G22599C, C23039G No. of seqs: 7(South Korea 1 USA 6) First: EPI_ISL_19412137, USA, 2024-7-9 Latest: EPI_ISL_19419687, USA, 2024-8-29 [usher](https://nextstrain.org/fetch/genome-test.gi.ucsc.edu/trash/ct/subtreeAuspice9_genome_test_e780_a689d0.json?label=id:node_5506868)...

S:346
KP.3.1.1
3' UTR

KP.3.3+C25703T(Orf3a:P104L)+T21737C, G29260A(S:F59L) GISAID query: C25703T, T21737C,G28884C No. of seqs: 8(Moldova 4 USA 1 Denmark 3) First: EPI_ISL_19357674, Moldova, 2024-7-3 Latest: EPI_ISL_19357681, Moldova, 2024-8-10 [usher](https://nextstrain.org/fetch/genome-test.gi.ucsc.edu/trash/ct/subtreeAuspice1_genome_test_22b66_d2aad0.json) ![image](https://github.com/user-attachments/assets/9d15b661-2b3d-4045-9aa8-648c30f691b0)

Rapid review needed
Emerged in an undersampled area
S:59
KP.3.3

KP.2.3+del21653_21655(S:S31-)+C28714T+C1528T, T21756A(S:F65Y) GISAID query: T21756A,G25593T,-16768 No. of seqs: 22(Canada 4(AB,BC,QC), UK 3 France 9 Iceland 1 Moldova 1 Netherlands 2 USA 2(NY,TN)) First: EPI_ISL_19312625, France, 2024-5-29 Latest: EPI_ISL_19441087, France, 2024-9-9...

New mutations
Convergent evolution
Usher
KP.2.3
S:65