likelihood ratios (and associated CIs) from pROC

[yhpua]

I'm writing to ask if it is possible to add "positive and negative likelihood ratios" to the ret arg of ci.coords()?

Thank you for pROC and for considering my request!

[xrobin]

Thanks for the request, it should be feasible. Do you have a reference for the exact formulas to calculate these 2 ratios?

[yhpua]

Thank you for your kind consideration.

To compute the CIs, the 2 oft-cited references are as follows:

Simel DL, Samsa GP, Matchar DB. Likelihood ratios with confidence: sample size estimation for diagnostic test studies. J Clin Epidemiol. 1991;44:763–770. doi: 10.1016/0895-4356(91)90128-V.

Martín-Andrés A, Álvarez-Hernández M. Two-tailed approximate confidence intervals for the ratio of proportions. Stat Comput. 2014;24:65–75. doi: 10.1007/s11222-012-9353-5.