DiaNN

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How to get the pr.matrix.tsv from the main out by the user?

3

Hi Vadim Thanks for your work! I used diann-1.8.1 in linux. I want to reproduce the pr.matrix.tsv from the main out. As you mentioned here:  `using global...

xiaoxHuang

Can't cross-run

1

The following warnings or errors (in alphabetic order) were detected at least the indicated number of times: WARNING: QuantUMS requires 6 or more runs for the optimisation of its hyperparameters...

Lin-apple

Inquiry on Distinguishing Alternative Isoforms with DIA-NN

3

First and foremost, I would like to thank you for developing the fantastic DIA-NN tool. I am currently working on a project where I aim to distinguish and quantify isoforms...

Takwon-Yoo

Malformed Library tsv files when Gene ID at the end of fasta description

3

There is an issue w/ DIANN when using the --gen-spec-lib flag to generate a library when the gene ID is at the end of a fasta description. Concretely, if the...

SeereouslyDrewNichols

Clarification on Identification and Quantification Numbers in DIANN

1

I hope this message finds you well. I am reaching out with a few questions regarding the identification and quantification of proteins and peptides using DIANN. I have noticed that...

hahahahhhhahaha

Quantity.Quality

8

Dear Vadim, I would have some questions about the Quantity.Quality. In a previous discussion (https://github.com/vdemichev/DiaNN/discussions/764), you explained this parameter can filter the precursors and keep the high-quality ones. You even...

NicoDrou

How to combine same sample (tech replicate) direct DIA data (.raw files from thermo) on DIANN to generate consolidate final results ?

4

rasharma24

Can DIA-NN detect non-standard amino acids

4

Hi Vadim, Thanks for providing the exceptional software for the community. I have a question about whether DIA-NN can detect proteins/peptides containing non-standard amino acids? If yes, what will be...

lmin-2023

1.9.x Linux/GLIBC_2.28 version

2

Hello, Any plans on releasing 1.9.x Linux binaries compatible with glibc 2.28? -Chris

downrange75

It doesn't work when I using the AlphaPeptDeep library to analyze my Dimethyl-labeled DIA data

1

Hi vdemichev, I predicted the dimethyl-labeled library with the AlphaPeptDeep and analyzed my Dimethyl-labeled DIA data using the predicted library on the DIANN-1.8.1. However, it just run one file and...

ningzaizai