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`annotate seqvars` tsv export transcript selection is not apparent

Open Nicolai-vKuegelgen opened this issue 11 months ago • 0 comments

Is your feature request related to a problem? Please describe. The mehari annotate seqvars command with the --path-output-tsv option, will always select a single transcript even with the implied default --pick-transcript-mode "all". The criteria for this selection are unclear and will - at least in some circumstances - not select the Mane transcript.

Describe the solution you'd like Ideally there should be a clearly defined order for selecting transcripts for the tsv output that also follows an order one could give via the --pick-transcript flags. Alternatively the --path-output-tsv could also require definition of --pick-transcript.

Describe alternatives you've considered At the minimum mehari should give a warning when the --path-output-tsv option is used without --pick-transcript-mode first, to indicate that (an unspecified) transcript selection is taking place.

Nicolai-vKuegelgen avatar Jan 21 '25 13:01 Nicolai-vKuegelgen