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Add 'PBS()'

Open atongsa opened this issue 1 year ago • 9 comments

PBS (population branch statistics) [^1] is derived from Fst, which can detect positive selection signals in admixted populations .

the formula is

T = - log(1 – FST)

PBS = (T_TH + T_TD − T_HD) / 2

[^1]: Yi, X. et al. Sequencing of 50 Human Exomes Reveals Adaptation to High Altitude. Science 329, 75–78 (2010).

atongsa avatar Feb 27 '23 07:02 atongsa