msprime icon indicating copy to clipboard operation
msprime copied to clipboard

Simulate genealogical trees and genomic sequence data using population genetic models

Results 109 msprime issues
Sort by recently updated
recently updated
newest added

Docs for the following `Demography` methods: [`add_population_split()`](https://tskit.dev/msprime/docs/latest/api.html#msprime.Demography.add_population_split), `add_admixture()`, `add_mass_migration()`, `add_migration_rate_change()`, `add_simple_bottleneck()`, `add_instantaneous_bottleneck()`; all have problematic formatting of types in the parameters section. In addition, they all accept either an integer...

The docs for `msprime.sim_ancestry` say that ploidy defaults to 2, yet the function defaults to `None`. It would be preferable if the function default were acutally 2, especially for people...

Msprime is much slower than MaCS when simulating long genomes/lots of recombination, as we've seen with the BosTau model in stdpopsim. There may be some low-hanging fruit in making this...

Performance

This would make a nice tutorial, as discussed in #1687, by simulating over a range of smallish values and extrapolating.

documentation

It would be useful to have a method that would combine two or more RateMaps and return an iterator over the distinct intervals at the rates. So, in usage, it...

enhancement

I have all permission to share our scripts to simulate genome with variation (piecewise) of selfing and dormancy. @jeromekelleher, let me know how to proceed. Since it's all rescaling we...

enhancement

Here's a small three population example without recombination. ```sh # ms.sh $MS 2 1 \ -t 1.0 \ -I 3 1 0 1 \ -em 0.0 3 2 1.0 \...

Performance

There's some typos in the commands, and ``asv run HEAD^!`` works better for me than the first command given.

documentation

We should provide simple methods for reading/writing RateMaps in binary and text formats. These should use numpy methods only, we don't need anything like zarr here. This is separate to...

enhancement