Trent Hauck

@abearab I've seen it, but not used it. I am a fan of those packages in R (e.g. granges). I also know there's some other analogues in Python for some...

100% -- you can actually do a little of granges stuff via SQL joins, but it's not quite as intuitive or as specialized to genomic intervals. E.g. say you ran...

It's a very nice package overall, and to your point would make for a good reference to build a "recipe" list from. To your question, depending on the end goal,...

@abearab, cool, that makes sense to me... I just updated biobear on pypi with the new quality score function as well as an alignment_score function that does basic local alignment...

Ah, ok, glad you got it. Looks like I have a little work to do dependency-wise.

Hey @abearab -- apologies for taking a bit to get onto this. The CRAM scanning feature is done, and I go started on the writing (though need some feedback from...

I have something in this [branch](https://github.com/wheretrue/exon/compare/add-regex-with-position?expand=1) I hope to finish up tomorrow. It's slightly different than locate as it requires a regex right now, but is relatively close... e.g. ```...

@abearab I updated biobear to support `locate_regex` as shown above. You can see how it looks through biobear/polars here: https://github.com/wheretrue/biobear/blob/5d9a8814ff925eaa850d21954e4602d03581418b/python/tests/test_session.py#L43-L68. Please let me know if you have any feedback on...

Cool, that all sounds good to me, no rush for me. Please just "at" me on this issue if/when you use this for your work if you have any thoughts...

Thanks again for the filing these issues. For the first, without loading everything into memory, you can stream through the `RecordBatchReader` from pyarrow like so: ```python import biobear as bb...