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[Question] Understanding why CLR -> Correlation is not compositionally-valid

Open jolespin opened this issue 2 years ago • 1 comments

A colleague of mine asked me why use proportionality when they could instead use CLR transformation followed by Pearson/spearman/biweight midcorrelation. I vaguely remember reading why this isn't compositionally-valid but I can't seem to recall the exact details on why this shouldn't be pursued and can lead to spurious associations.

jolespin avatar Dec 21 '22 22:12 jolespin

Hi @jolespin There is actually an nature issue about this : https://doi.org/10.1038/s41592-020-01006-1

suzannejin avatar Feb 01 '24 11:02 suzannejin