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samd21/samd51 UART do not support hardware flow control
The SAMD21 and SAMD51 UART implementations do not support hardware flow control.
It turns out this is necessary for boards that have an attached NINA/ESP32 co-processor to be able to support using that processor as a Bluetooth HCI.
See https://github.com/arduino/nina-fw/blob/master/main/sketch.ino.cpp#L121-L128
Support for SAMD21 is now ready merged into dev and https://github.com/tinygo-org/tinygo/pull/4077 ready for review.
Completed with v0.31.0 so now closing. Thank you!