A question about cr.pl.circular_projection parameter "normalize_by_mean"

[yulicarp]

Hi,

Thanks for this amazing work!

I have a questions about using the parameter normalize_by_mean set to True. When I focus the early cells terminal fate probabilities and try to interpret it trajectory fate, it seem different from the results using another function cr.pl.aggregate_fate_probabilities. Here are the results I got using different methods.

when "normalize_by_mean" set to True, it seems HSC_MPP was MKP and NeuP bias. But when normalize_by_mean set to False, it seems HSC_MPP was ProB bias and same to cr.pl.aggregate_fate_probabilities results.

Could you tell me how to interpret these results? i am really confused.

1. when "normalize_by_mean" set to True

2. when "normalize_by_mean" set to False

3. when using cr.pl.aggregate_fate_probabilities