ALLHiC
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overestimated Chromosome size.
Hi, Prof. Zhang,
Recently, i have a dipolid geome (2n=12) project. And it has 1.7% heterozygosity. Fisrt, i removed redundant sequnces using purge_haplotigs. Then, these contigs were scaffolding using ALLHIC. However, a overestimated, approximately 400 Mb, chromosme size was obtained. What should i solve these issues.
Could you please provided some suggestions for me how to assemble diopolid genome with the high heterozygostity.
Thx Hongbing