Sam Wolock

Hi @aopisco, apologies for the delayed response. Would you mind clarifying when exactly you are getting this error? I can reproduce the error as you suggested (`from numpy.lib.arraypad import _validate_lengths`),...

The doublet rate should scale linearly with the number of cells loaded, so based on the user guide, I'd expect a doublet rate of ~0.15 for your sample with ~21k...

Hi @grst, There are likely several factors at a play here. Apologies in advance for the lengthy response. First, a couple of asides: 1. The automatic thresholding of the simulated...

Great, those Scrublet results seem much better. The Scrublet UMAP does look a bit pathological... I wonder if re-running it (with a different random state) or simply zooming in on...

Hi @MichaelPeibo, Except for experimental methods for doublet detection (e.g. cell hashing), I don't know of any truly independent ways to validate the predicted doublets. That said, if you know...

Hi Dan, `TruncatedSVD` is automatically used in place of `PCA` when you supply `mean_center=False` for `scrub_doublets()`. Here's the relevant section of the docs: ```python log_transform : bool, optional (default: False)...