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cutoff parameter does not limit number of cells chosen

Open kpruss opened this issue 1 year ago • 0 comments

I have not been able to successfully implement a cut-off threshold while calling Scissor.

For example, if alpha = 0.05 leads to 40% of cells being selected by Scissor and I want to decrease the proportion of Scissor-selected cells

cutoff_threshold = 0.2 alpha_threshold = 0.05

info <- Scissor(bulk_dataset = duod_counts, sc_dataset = seur_duod, phenotype = phenotype, alpha = alpha_threshold, cutoff = cutoff_threshold, tag = tag, family = "gaussian", Save_file = paste0('sbatch_outputs/grid_search/', date, alpha_threshold, "_", cutoff_threshold, protein, '.RData'))

The number and identity of cells selected is exactly the same as that chosen without the inclusion of the cutoff parameter.

kpruss avatar Aug 16 '22 17:08 kpruss