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Tacox plugin: Sequence mismatches on multiple scaffold on random sequence
Affects: tacox plugin: Cadnano design files with multiple scaffold strands, double stranded sections that use the scaffold
Problem:
- It is only possible to select a single scaffold sequence.
- either if a single sequence is selected or the random sequence is used
the sequences of the other scaffold bases will be completely random, not matching the staple strands (see picture: first scaffold with correct pairs (green), second scaffold with mismatches (red)
Expected behaviour: the tacox plugin should not silently create mismatching duplexes.
- either assign matching random sequences for other then the first scaffold
- or disallowing designs in the multiple scaffolds altogether