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Arriba for plate-based scRNA-seq

Open Silvia-Bio opened this issue 11 months ago • 2 comments

Hiya,

Can Arriba be used to detect fusions in single-cell RNAseq data (e.g. Smart-seq2). I expect to see a greater number of false positives compared to bulk RNAseq, and with a lower number of reads supporting the fusions. I'm wondering what parameters should be optimized for scRNAseq data, and how the list of candidate fusions should be further filtered.

Thank you,

S.

Silvia-Bio avatar Jul 25 '23 21:07 Silvia-Bio