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interpretation of 'fident' output

Open LLehner opened this issue 8 months ago • 2 comments

Hello, thank you for this great tool.

Currently we are trying to redo the HFSP curve using foldseek instead of mmseqs2. When using identical data we noticed a shift downwards in % sequence identity using foldseek compared to mmseqs2.

My question is: Is 'fident' reported by foldseek based on the AA residues in protein sequences (like mmseqs2) or is it based on the new structural alphabet of 3Di states?

Edit: we noticed a downwards shift in foldseek, not upwards, in terms of % sequence identity

LLehner avatar Jul 02 '24 16:07 LLehner