Noel Southall
Noel Southall
Want to open a general issue as a dumping ground for some random items potentially related to the stitcher manuscript
Many resource names are hardcoded in the java code e.g. ``` public class GSRSEventParser extends EventParser { public GSRSEventParser() { super ("G-SRS, April 2020"); } ``` The EventParser classes in...
INFO: ################ UNTANGLE COMPONENT 1258 of size 43698... 254/100116 That's great that we can untangle such awful messes. Do we want some pre-component filter step to avoid having to wade...
Rancho and Broad have clinical-stage compounds that don't have UNIIs or are not found in GSRS CI-185,282 ICI-185,282 OC(=O)CCC\C=C/C[C@@H]1CO[C@@H](O[C@@H]1c1ccccc1O)C(F)(F)F Phase 1 thromboxane receptor antagonist https://stitcher-dev.ncats.io/api/stitches/latest/ICI-185,282 We can do two things...
Acetyl Ceramide https://stitcher-dev.ncats.io/api/node/368395 Has markup by Rancho, but lives on its own stitch node at present. Can we prioritize likewise orphans with rich synonym list, lychi L3 links and target...
Seems like a reasonable idea to combine google Sheet with a curation UI to help mobilize manual curation effort against prioritized, specific groups of issues.
If you filter to principle substances that are antiviral, oseltamivir is NOT included, but it is included if you list all substances. https://drugs.ncats.io/substances?q=(comments:%22Pharmacologic%20Substance%5BC1909%5D%7CAnti-Infective%20Agent%5BC254%5D%7CAntiviral%20Agent%22)%20AND%20(%22oseltamivir%22)&facet=Development%20Status%2FUS%20Approved%20Rx&page=1 https://drugs.ncats.io/substances?q=(comments:%22Pharmacologic%20Substance%5BC1909%5D%7CAnti-Infective%20Agent%5BC254%5D%7CAntiviral%20Agent%22)%20AND%20(%22oseltamivir%22)&facet=Development%20Status%2FUS%20Approved%20Rx&facet=Substance%20Form%2FPrincipal%20Form&page=1 The principle substance for that drug...
2-AMINO-3-HYDROXY-BUTANOIC ACID 760PJT2SS0 is merged with an NPC entry for threonine --- what a mess See also: https://stitcher.ncats.io/api/stitches/v1/2ZD004190S NPC entry should likely be replace with stereo-specific structure to fix?
caodac:hamster: 2:42 PM. June 9, 2020 on the next build we should include chebi
The parent drug should probably be merged with its isotopically-enriched form, if only the latter is marketed. Florbetapir https://drugs.ncats.io/substances?q=%22FLORBETAPIR%20F-18%22&facet=Substance%20Form%2FPrincipal%20Form