Compatibility of hdWGCNA with Visium HD Data

[wnddl111]

Hello,

I am interested in using the hdWGCNA package with Visium HD data. Firstly, I would like to confirm if this is possible.

While attempting to proceed on my own, I encountered an issue due to the absence of the required metadata in my dataframe. Specifically, the package requires 'row', 'col', 'imagerow', and 'imagecol' columns.

Could you please clarify what is meant by the 'row' and 'col' columns in this context?

Regarding 'imagerow' and 'imagecol', I am considering using the 'x.coordinates' and 'y.coordinates' obtained from the Loupe Browser export CSV. Would this approach be acceptable?

Your guidance on how to properly prepare my dataframe for hdWGCNA would be greatly appreciated.

Thank you for your assistance.

Best regards, juyoung lee