Stephen Larson issues

Results 81 issues of


                                            Stephen Larson

Produce Channel B I/V curve comparison figure

Compare the current voltage relationship of a key ion channel to what is created by our simulated version in the model.

Produce neuron electrophysiology figure C + compare to simulated match

Compare a third key neuron's electrophysiology data with that collected optically.

Produce neuron electrophysiology figure B + compare to simulated match

Compare a second key neuron in simulation to that in real recordings; probably collected optically.

Produce neuron electrophysiology figure A + compare to simulated match

Would show a key simulated neuron, perhaps AVAL/R, and compare its electrophysiology activity to recorded activity (probably optical)

Produce muscle force vs simulated match figure

Would compare muscle force produced by Sibernetic model with real measurements during behaviors. Similar figure appears in a Cohen paper.

Produce biophysics parameter figure + simulated match

Some property of the physics of the model in sibernetic to feature. Candidates could include elasticity, Young's modulus. Compare with simulated biophysics

Produce Behavioral Figure D + simulated match

Forward crawling - wild type Sibernetic + c302

Produce Behavioral Figure C + simulated match

Forward swimming in a wild type. Sibernetic + c302

Produce Behavioral Figure B + simulated match

Forward crawl with proprioception - wild type This involves using Sibernetic + c302.

Generate outline of what is the model and basic facts about c. elegans neurophysiology

- How synaptic transmission works and what model we are using? - What ion channel models are we using or want to use? - Gap junctions - Chemical synaptic channels...