how to import raw data into Sirius

[yifanhh]

Hi, all. I hope to know how to import raw data (or spectrum) into Sirius app. The MS data was acquired in agilent Q-TOF

[backInTheChemLab]

Not sure if it's too late, but the way I found is to first process the data on MassHunter and export the data as a .cef file.

That file can then be imported into the Sirius app

[mfleisch]

SIRIUS 6 does not have raw format support. Common workflows to process raw data are:

• raw format -> msconvert -> .mzml -> SIRIUS (preprocessing is performed by SIRIUS)
• raw format -> MassHunter -> .cef -> SIRIUS (preprocessing is performed by MassHunter)
• raw format -> MZmine -> Eport To SIRIUS -> .mgf -> SIRIUS (preprocessing is performed by MZmine)
• raw format -> MS-DIAL -> Eport To SIRIUS -> .mat -> SIRIUS (preprocessing is performed by MS-DIAL)

Some of this tutorials also cover this topic: https://youtube.com/playlist?list=PL8R4DKiWsw-tIG8w3hZWJunWZyy-qnIZM&si=4iDXS2ifTaMd7n_F

Many Verdor tools can export mzml these days, which is also a valuable option.