seqan
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a feature request (inter-chromosomal structural variants) for mason_variator
I have used mason_variator to simulate different types of structural variants. The problem is that I need simulations for inter-chromosomal translocations and indels given two chromosome A and B. For instance, some sequences are selected from A and moved to B and information about this mutation would be like A[position with respect to the original A chromosome, length], B[position with respect to the original B chromosome, length].
I satisfied with the current implementation in terms of user-friendliness with respect to intra-chromosomal events.
Thanks in advance.
@holtgrewe can you have a look? Thank you.
I think that this is a very important point. Its impact on the Mason could would be quite large and I will have to look into this and see what has to be changed to make it work.
Did this feature ever get implemented?
No, it did not. I will probably not have the time to go for this.