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bmcite progenitor cell types
I am trying to sort bone marrow cells into these categories:
celltypes <- c("HSC/MPP", "LMPP", "CMP", "CLP", "GMP", "MEP")
In bmcite, there are some progenitor cells labelled differently: Prog_B 1
, Prog_B 2
, Prog_DC
, Prog_Mk
, andProg_RBC
.
[1] "Prog_RBC" "GMP" "Prog_B 2" "Prog_Mk" "HSC" "LMPP" "Prog_DC" "Prog_B 1"
From my understanding:
-
Prog_RBC
can be recoded as "MEP" -
Prog_Mk
can be recoded as "MEP" -
Prog_B 1/2
can be recoded as "CLP" -
Prog_DC
can be of either myeloid (CMP) or lymphoid (CLP) lineage
Is there anything in the generation of this dataset or cell type labelling that dictates whether the Prog_DC
in this dataset should should be recoded as from myeloid or lymphoid?
I have the same confusion, does anyone know?