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Published 20 hours ago • verified publisher icon satijalab

Spatial transcriptomics

Open alextamburino opened this issue 5 years ago • 1 comments

Hi @ChristophH @satijalab

Not an issue - but would appreciate your input. Would it be appropriate to create a Seurat object with Spatial Transcriptomics data and use SCTransform to normalize it?

Thanks in advance!

Alex

alextamburino avatar Sep 23 '19 12:09 alextamburino

Hi Alex, I cannot comment since I have not had a chance to look at Spatial Transcriptomics data. But I'd assume that it looks quite different from droplet based UMI scRNA data and needs its own specific normalization methods.

ChristophH avatar Sep 25 '19 09:09 ChristophH