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JN.1.4 + N:R40H & ORF9b:V37I (46 seqs, 4 countries)

Open arodzh-sudo opened this issue 1 year ago • 1 comments

Sub-lineage of: JN.1.4 Substitution on top of JN.1.4: N:R40H + ORF9b:V37I Earliest sequence: 2023-12-19, New York, USA — EPI_ISL_18756904 Most recent sequence: 2024-02-04, New York. USA — EPI_ISL_18921031 Countries circulating: Puerto Rico (20), USA (10) [4 CO, 3 NY, 2 TX, 1 OK], France (1), Canada (1) Number of sequences: 32 GISAID nucleotide query: C774T, C28311T, G28392A CovSpectrum query: JN.1.4* (Nextclade) + N:R40H, ORF9b:V37I

EPI_ISL_18756904,EPI_ISL_18782492,EPI_ISL_18817626,EPI_ISL_18837455,EPI_ISL_18837488,EPI_ISL_18847344,EPI_ISL_18862100,EPI_ISL_18869580,EPI_ISL_18869633,EPI_ISL_18916988,EPI_ISL_18916989,EPI_ISL_18917018,EPI_ISL_18917049,EPI_ISL_18917050,EPI_ISL_18917051,EPI_ISL_18917070,EPI_ISL_18917071,EPI_ISL_18917079,EPI_ISL_18917080,EPI_ISL_18917081,EPI_ISL_18917082,EPI_ISL_18917083,EPI_ISL_18917084,EPI_ISL_18917085,EPI_ISL_18917086,EPI_ISL_18917087,EPI_ISL_18917088,EPI_ISL_18917089,EPI_ISL_18917090,EPI_ISL_18921031,EPI_ISL_18927928,EPI_ISL_18927959

Screenshot 2024-02-27 at 13-35-11 Nextstrain _ fetch _ genome ucsc edu _ trash _ ct _ singleSubtreeAuspice_genome_108a6_e0e160 json

Both mutations are estimated to increase fitness

Nmut orf9bmut(1)

arodzh-sudo avatar Feb 27 '24 17:02 arodzh-sudo