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Published 20 hours ago • verified publisher icon samtools

Possible 4x speed up of merge --gvcf ref.fa

Open pd3 opened this issue 4 months ago • 1 comments

This needs to be tested, but it appears that merge --gvcf ref.fa is 4x slower than merge --gvcf -. This may be caused by inefficient use of faidx_fetch_seq; would pre-loading and caching the reference sequence help?

pd3 avatar Feb 21 '24 15:02 pd3