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liana multi df_to_lr function using precomputed pseudobulk Differential Expression results

Open gianfilippo opened this issue 8 months ago • 2 comments

Hi,

I did most of my analysis using Seurat and the cell type specific pseudobulk differential expression using Muscat.

I can read and process the Seurat object exported as AnnData.

For consistency, instead of recomputing the differential expression with pydeseq2, I loaded the Muscat results and replaced colnames with names consistent with pydeseq2 results. I should point out that most, but not all columns are present.

Is it ok to use the imported DEG as input to the liana multi df_to_lr function ?

Thanks

gianfilippo avatar Feb 11 '25 06:02 gianfilippo