Enable/disable any pane's function in preferences
Seeking means to enable/disable each pane, similar to the enable switch on the quick throw pane.
The main reason to have that checkbox is to allow me to provide some default values without it being invasive to a user that doesn't want that functionality.
I can see where it would be nice to have this to have a little more control over what's going on in the app at a given time, but I think that most users will configure the app a certain way at first and will not continually reopen the prefs to toggle things once they get their workflow down. But, if a lot of people want this then I could see prioritizing it.
I mentioned this to rapidly kill the Ctrl+Alt+Arrows crossover between this app and text boxes (mentioned in different issue), but deleting all of the keyboard shortcuts wasn't a big deal (but i'll have to nuke the settings back to defaults if I wonder what one used to be).
None of this is a notable deal, as you said.