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Disruption after load files

Open ccmeth opened this issue 1 year ago • 8 comments

Hi, developers,

I met with an issue related to load_contacts. After I load hic matrix, the R studio became disrupted and I could do nothing, could not save the data.

image

Could you please give me some suggestions? Thanks!

ccmeth avatar Oct 24 '23 07:10 ccmeth

Hi there, Do you have sufficient memory to load the data into the session? Does it work for larger resolutions, like 1Mb?

teunbrand avatar Oct 24 '23 07:10 teunbrand

Hi there, Do you have sufficient memory to load the data into the session? Does it work for larger resolutions, like 1Mb?

1Mb also does not work for me. However, several days ago, I could used load_contacts without problem. image

ccmeth avatar Oct 24 '23 08:10 ccmeth

image I don't think this issue is associated with memory size. After loading high-resolution (5kb) hic data, my free memory is still 41G,

ccmeth avatar Oct 24 '23 08:10 ccmeth

Furthermore, previously, I also met with another open issues (cannot load the second .hic) reported by other person. The first .hic could be successfully loaded but the second failed (no error message displayed, but I could no nothing: R studio disrupted), therefore I needed to save the first matrix immediately after loading, then close R studio, restart R studio and load the second .hic files.

ccmeth avatar Oct 24 '23 08:10 ccmeth

I'm unsure about what causes this issue. Is it 1 file that doesn't work or other files also don't work?

several days ago, I could used load_contacts without problem

That doesn't make it easier to debug, as it points towards something being a cause of the issue that doesn't live in genova.

teunbrand avatar Oct 24 '23 08:10 teunbrand

Yeah, it's very strange. I tried several times but load was always not success even at low resolution (1Mb). However, another .hic files with high resolution (10kb) was success. The size of two .hic files was similar.

ccmeth avatar Oct 24 '23 09:10 ccmeth

When the load process was not successful, I could not close R studio normally and need to quit with "force". I noticed that although R studio was closed, after checking "top" in terminal, rsession process was still ongoing.

ccmeth avatar Oct 24 '23 09:10 ccmeth

I would check the number of open files limit for your RStudio Server instance. I ran into an issue where the RStudio Server I was using had a very low limit on the number of open files and then after loading the HiC file my RSession would become unusable.

LucasMcNU avatar Jan 26 '24 16:01 LucasMcNU