Can we determ the chromatin accessibility for one single cell?

[biozzq]

Dear all，

I have a basic question. In many published papers, I found that they usually describe the binary nature of scATAC data, also in your paper-(A bin with value “1” indicates that one or more reads fall within that bin, and the value “0” indicates otherwise.). I don't know why we can't use the reads number to determ the chromatin accessibility for one single cell, and not just open or closed. How do you think that? thank you in advance.

sincerely Zheng zhuqing