Young-mok Jung

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This is a good point. It is true it takes long to load all indexes with low disk I/O. I assume you might be loading indexes from HDD disk, where...

I like to share the numbers I got with option 1. ```sh Tested on 150MB/s hdd , Intel(R) Xeon(R) Silver 4208 CPU @ 2.10GHz, --------------------------------------- RMI models: 54 sec (~10GB)...

I ran some benchmarks regarding mimalloc and below are the results. Env: Intel(R) Xeon(R) Silver 4208 CPU @ 2.10GHz, 16 physical core (32vCPU) Dataset: single-end ERR194147_1.fastq Config: 32 threads **Findings:**...

We will update the mimalloc and readme within a few days! I'll notice it here as soon as it's updated. That's an interesting point, thank you for sharing your tips.

My PR in Bioconda package was merged few hours ago, now BWA-MEME uses mimalloc as default (also the master branch).

Thank you for your valuable tips and suggestions! We really appreciate it. To summarize, 1) pipeline of (alignment, fixmate, reheader, sort) results in low CPU utilization (bottleneck on sorting operation)....

Edit: Samtools sort have higher throughput in general, using mbuffer (same amount of buffer used for samtools sort) would resolve the `write hang` issue described below. Hi, I recently looked...

Sounds great! I believe there are various cases to consider before changing to pipelined version. I look forward to the updates. Thank you

Hi, I drew it using Microsoft Excel! I modified the CDF code in pensieve

Hi, To plot CDF I modified this code(https://github.com/hongzimao/pensieve/blob/master/test/plot_results.py) I normalized the QoE (total reward divided by number of video chunks) the axis name should be changed to normalized QoE, sorry...