RNA velocity : loom integration for multiple batches

[anshu957]

Thank you for the excellent and very comprehensive tutorial ! I would like to know one specific thing about RNA velocity. In the tutorial, it is mentioned that the second case (of batch corrections) becomes important for RNA velocity analysis and I was wondering if you have any guidance on how to carry out such analysis. For instance, I've sc-RNAseq data coming from multiple batches which is then processed to get a batch-corrected cell state clustering. Now, for the RNa velocity, I've generate 6 loom files (each coming from a different batch) using velocyto package and I combine them together and then finally merge the combined loom file to the processed Andata object. Is this the right approach or do I need to be careful about batch corrections when combining individual loom files ?