talking-head-anime-2-demo
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can't install wxPython on Ubuntu
There is not wxPython4.1.1 whl file about linux
pip install -U -f https://extras.wxpython.org/wxPython4/extras/linux/gtk3/ubuntu-16.04 wxPython
this could work
If 4.1.1 does not work, you can try an older version. The code does not use that many features from wxPython, so a version that is quite recent is fine. I would say anything past 4.0 would work as well.