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Run with converted gnomAD v4.0.0 dataset fails

Open tcrevier opened this issue 3 months ago • 2 comments

Running against the gnomAD v4.0.0 (converted with CRISPRme) fails in the Integrating Results phase.

Error message

Traceback (most recent call last): File "/opt/conda/opt/crisprme/PostProcess/./resultIntegrator.py", line 492, in if float(elem) == 0: ValueError: could not convert string to float: 'rs635634' CRISPRme ERROR: result integration failed (script: /opt/conda/opt/crisprme/PostProcess/post_process.sh line 45) CRISPRme ERROR: postprocessing failed - reference (script: /opt/conda/opt/crisprme/PostProcess/submit_job_automated_new_multiple_vcfs.sh line 848)

Some details

I ran a guide with a set of parameters against the hg38_1000G VCFs successfully and wanted to also run the same against gnomAD VCFs. I downloaded the VCFs and converted them and then ran again with the same parameters but updated the sampleIDs to be the gnomAD sample IDs and VCFs to be the gnomAD VCFs. I get the error that is above. I am running on a fresh Ubuntu VM with 128 GB of RAM against the latest docker. I have reproduced the error twice.

tcrevier avatar Mar 28 '24 16:03 tcrevier