Loading a saved minder file will move all of the Nodes if the minder is extensive enough (enough nodes and subnodes)

[TheRobberPanda]

My minder has 12 main nodes, and many, many child nodes. Every time I reload the file, I have to manually rearrange all the nodes because they move on their own.

The steps for replication are simple, make a minder file with enough nodes. And save it, reopen it and you will see the nodes have moved

[phase1geo]

What node layout are you using for the trees (the setting is in the map sidebar panel)? It's probably either "horizontal", "to right" or "manual" based on the portion of the image above.

[TheRobberPanda]

"horizontal"