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Flux rate vs concentration units

Open AgustinPardo opened this issue 3 years ago • 0 comments

Please include a short description of problem here

hello,

I am using a model that is in m7H10 medium:

The "model.medium" I is: {'EX_ca2': 1000.0, 'EX_cit': 1.0, 'EX_cl': 1000.0, 'EX_co2': 1000, 'EX_cu2': 1000.0, 'EX_fe2': 1000.0, 'EX_fe3': 1000.0, 'EX_glu_L': 1.0, 'EX_h2co3': 1000, 'EX_h': 1000, 'EX_k': 1000, 'EX_mg2': 1000.0, 'EX_na1': 1000, 'EX_nh4': 20, 'EX_o2': 20, 'EX_pi': 1000, 'EX_so4': 1000, 'EX_ac': 10, 'EX_pydxn': 1, 'EX_mobd': 1000, 'EX_btn': 1}

The bibliography m7H10 media composition is:

Composition (Ingredients (g/L)) Ammonium sulfate, 0.50 Monopotassium phosphate, 1.50 Disodium phosphate, 1.50 Sodium citrate, 0.40 Magnesium sulfate, 0.025 Zinc sulfate, 0.001 Copper sulfate, 0.001 L-Glutamic acid, 0.50 Ferric ammonium citrate, 0.04 Pyridoxine hydrochloride, 0.001 Biotin, 0.0005 Malachite green, 0.00025 Agar, 15.00

I don't understand how they made the conversion from g/L to mol/gcdw/h. Because one is a concentration and another is a flux rate.

Is there an standar on COBRA of which units use the inputs, that is "mol", "gCDW" ,"hour", "M", "molar concentration"?

I can't find any good explanation about the relationship between experimental values units and input values of the COBRA model. Does anyone know a good bibliography?

Regards

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AgustinPardo avatar Sep 24 '20 16:09 AgustinPardo