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phase_common failing at PBWT step

Open nmshahir opened this issue 10 months ago • 2 comments

I'm using SHAPEIT5 to phase a large panel (300K+) using phase_common and it keeps stopping at the PBWT step? This is the relevant error:

WARNING: No PBWT states found [1000042 / w=76] / Using 100 random states

WARNING: No PBWT states found [1000042 / w=77] / Using 100 random states

ERROR: Haploid underflow impossible to recover for [1000039]

The parameters used are below:

Parameters:

  • Seed : 15052011
  • Threads : 8 threads
  • MCMC : 15 iterations [5b + 1p + 1b + 1p + 1b + 1p + 5m]
  • PBWT : [window = 4cM / depth = auto / modulo = auto / mac = 5 / missing = 0.1]
  • HMM : [window = 4cM / Ne = 15000 / Recombination rates given by genetic map]

Please advise?

nmshahir avatar Apr 09 '24 09:04 nmshahir