obo-relations
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relax range constraint on regulates
change from process to process or characteristic
(there are other tickets to be linked here but I can't find them)
This change is necessary for go-plus to be coherent (currently crytpic incoherence as not caught by elk 0.43)
alternative:
create three parallel relations and use these in GO for the RoBQ branch
The two alternatives are not mutually exclusive - I think it is most practical to first relax, then we can make the GO change. But this is actually quite urgent
what problem does that solve? by 'characteristic' do you mean, regulation of quality?
GO plus for example states that regulation of biological quality regulates a quality..

The other option would be to introduce new relations.
@pgaudet relates to this GO issue: https://github.com/geneontology/go-ontology/issues/16524
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