Can we safely have "characteristic of part of" capture physiological and anatomical phenotypes?

[matentzn]

From obo slack.

I asked: What is the risk of adding this role chain:

(characteristic of o occurs in) subPropertyOf characteristic of part of

to the existing ones:

(characteristic of part of o part of) subPropertyOf characteristic of part of
(characteristic of o part of) subPropertyOf characteristic of part of

@cmungall responded:

located_in is safer

In uPheno 2, it becomes increasingly clear that general grouping like

"abnormal cardiovascular system phenotype"

should capture both

• Increased heart phenotype (defined in terms of an anatomical structure in UBERON) AND
• increased cell proliferation in the heart (defined in terms of a GO process that occurs in the heart)

I think in order to enable this, we need to add the above role chain.

@cmungall can you explain how "located_in" fits into this?

[dosumis]

Potential problems with reasoning across part_of relationships between properties?

[matentzn]

Could you give an example, even if fictional?

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