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Review developmental relations

Open cmungall opened this issue 7 years ago • 1 comments

Continued from https://github.com/obophenotype/uberon/issues/1460

Thought we had a ticket for this...

The current defs are largely due to me. Currently we have an alternate proposal from @dosumis (can you post the link David?), based on continuity of cells. I think these can be combined. AFAICR David's proposal would have some problems with existing ontologies like ZFA where develops_from is used even when there is no cell continuity (e.g. cartilage replacement).

@alanruttenberg also points out issues with the direct form of this relation

cmungall avatar Oct 23 '18 03:10 cmungall

Here's a rather ancient, half written paper proposing a definition of develops_from and various sub-relations using cell lineage as a basis: https://docs.google.com/document/d/1M2Esis8NF9y-ADAIC7uoVPF1mMu-0Z4oeDEVjAQunLY/edit Comments are most welcome.

Note: The proposal includes a relation for templating (covering cartilage replacement) - but doesn't make it the superproperty. I suspect any retrofit required by ZFA to cope with this would be manageable.

@Clare72: I think it may be worth reviving this paper in light of pending work on neuronal lineages in FBbt.

dosumis avatar Oct 24 '18 12:10 dosumis