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patterns for phenotypes of total amount of a sporadic process/behavior, bout length and bout number

Open Clare72 opened this issue 2 years ago • 3 comments

e.g. sleep -increased/decreased total sleep (time spend asleep over total time) -increased/decreased bout number -increased/decreased bout duration

see https://github.com/FlyBase/drosophila-phenotype-ontology/issues/101 discussed on upheno call 2022-06-30 add other examples to this ticket

Clare72 avatar Jun 30 '22 16:06 Clare72

MP has abnormal sleep behavior (http://www.informatics.jax.org/vocab/mp_ontology/MP:0011396)

This has children like: fragmentation of sleep/wake states (MP:0009436) abnormal circadian sleep/wake cycle (MP:0020478) narcolepsy (MP:0020478) abnormal sleep pattern (MP:0001501)

There are a number of annotations about total time asleep that are attached to either abnormal sleep pattern or abnormal sleep behavior. The MP does not currently have a term for abnormal sleep duration but it looks like we should have one.

the fragmentation term is probably close to the increased sleep bout concept

sbello avatar Jun 30 '22 18:06 sbello

We currently don't have/want this for any other behaviors than sleep in dpo right now, but I think this could potentially be used for many other behaviors, such as feeding, grooming, courtship, etc. Curators may want terms for increased/decreased total amount of the behavior (within a time interval), increased/decreased number of times the behavior happens (within a time interval) and increased/decreased (average) duration of each episode of the behavior.

Clare72 avatar Jul 05 '22 12:07 Clare72

MP has terms for abnormal/increased/decreased grooming and looking at the annotations I see notes like

male mice exhibit more bouts of grooming and longer time grooming in a splash test compared with wild-type mice (MGI:6196014)

mice exhibit increased grooming bouts and spend more time self-grooming prior to lesion formation than do wild-type mice (MGI:3759301)

number of bouts of social grooming, in which one member of the pair grooms the other, is less in 21 day old mice (MGI:5763612)

So I would agree that more general patterns where different behaviors can be used would be helpful.

sbello avatar Jul 05 '22 14:07 sbello