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Fix carotid body classification: move from cardiovascular to peripheral nervous system

Open dragon-ai-agent opened this issue 4 months ago • 3 comments

Summary

This PR fixes the anatomical classification of the carotid body (UBERON:0001629) by changing its system membership from cardiovascular to peripheral nervous system, as requested in issue #3591.

Changes Made:

  • Changed part_of relationship from UBERON:0001530 (common carotid artery plus branches) to UBERON:0000010 (peripheral nervous system)
  • Added reference to PMID:32965908 which provides evidence supporting this anatomical classification
  • Added required metadata including dcterms-date, term_tracker_item for issue tracking, and created_by attribution

Rationale:

According to the current definition and evidence from PMID:32965908, the carotid body is "a sensory organ in the peripheral nervous system located in the adventitia of the bifurcation of the common carotid artery". While the structure is anatomically adjacent to the carotid artery bifurcation, it is functionally and developmentally not part of the cardiovascular system - it belongs to the peripheral nervous system as a chemoreceptive sensory organ.

Validation:

  • All UBERON IDs verified to exist and are not hallucinated
  • Syntax validation passed with robot convert
  • Maintains existing is_a relationship to UBERON:0034979 (nonchromaffin paraganglion)
  • Preserves spatial relationships with overlaps annotations for carotid arteries

Fixes #3591

@dragon-ai-agent

dragon-ai-agent avatar Aug 13 '25 14:08 dragon-ai-agent

This PR has not seen any activity in the past month; if nobody comments or reviews it in the next week, the PR creator will be allowed to proceed with merging without explicit approval, should they wish to do so.

github-actions[bot] avatar Sep 13 '25 02:09 github-actions[bot]

Looks like duplicate with #3595 Close?

dosumis avatar Sep 15 '25 13:09 dosumis

This PR has not seen any activity in the past month; if nobody comments or reviews it in the next week, the PR creator will be allowed to proceed with merging without explicit approval, should they wish to do so.

github-actions[bot] avatar Oct 16 '25 02:10 github-actions[bot]