Inner cortex of thyroid cartilage

[masciam]

Inner cortex of thyroid cartilage:

Synonyms

Definition (free text, please give PubMed ID)

Parent term (use https://www.ebi.ac.uk/ols/ontologies/uberon)

part of thyroid Your nano-attribution (ORCID) https://orcid.org/0000-0003-1940-6740

Comments : It is used in radiology to staging the tyroid cancer This is extracted from the AJCC7th edition " Imaging may be used as an important adjunct to identify the presence of submucosal extension, especially at the anterior commissure where lesions may spread anteriorly along Broyle’s ligament to involve the inner cortex of the thyroid cartilage. Imaging may also identify glottic carcinomas that have occult transglottic or subglottic spread. The normal paraglottic space is often diffi cult to routinely detect at the level of the true vocal cord due to the close apposition of the lateral thyroarytenoid muscle to the inner cortex of the thyroid cartilage. Tumor erosion limited to the inner cortex of the thyroid cartilage indicates a T3 lesion whereas carcinomas that erode the outer cortex of the thyroid cartilage defi ne a T4a tumor. Stage T4 (a and b) is diffi cult to identify based on clinical examination alone as the majority of the criteria cannot be assessed by endoscopy and palpation."

AJCC7thEdition.pdf

[dosumis]

Distinguishing inner vs outer cortext according to Perplexity:

The thyroid cartilage is composed of hyaline cartilage, which undergoes age-related ossification starting in adulthood25.

Outer region: Contains denser hyaline cartilage with a higher collagen matrix density, providing structural rigidity26. Serves as the attachment site for extrinsic muscles (e.g., sternothyroid, thyrohyoid) via the oblique line on the external surface23.

Inner region: Less mineralized, with a higher proportion of chondrocytes and proteoglycans for flexibility6. Directly supports the vocal ligaments and thyroarytenoid muscles210.

https://www.perplexity.ai/search/what-criteria-are-used-to-divi-9AEHvB5GQdejfsp34wgPkA

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