obophenotype
stratum corneum of esophageal epithelium
Preferred term label: stratum corneum of esophageal epithelium
Synonyms
Definition (free text, please give PubMed ID) The outermost layer of the stratified squamous epithelium lining the esophagus, composed of several layers of flattened, anucleated keratinocytes called corneocytes. It forms the primary protective barrier against mechanical, chemical, and microbial insults, while regulating permeability and contributing to tissue integrity. This layer is characterized by corneocytes embedded in a lipid-rich extracellular matrix, providing mechanical reinforcement and maintaining essential barrier functions of the esophageal lining.
doi:10.1038/gimo15 PMID: 21126700 PMID: 26019440
Parent term (use https://www.ebi.ac.uk/ols/ontologies/uberon)
non-keratinized stratified squamous epithelium
Your nano-attribution (ORCID) https://orcid.org/0009-0005-7919-4905
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@dragon-ai-agent please add this term. Make sure not to use the IDs
UBERON:7770000, UBERON:7770001, UBERON:7770002, or UBERON:7770003
I've created a new term 'stratum corneum of esophageal epithelium' with ID UBERON:8910024. The term is properly classified as non-keratinized stratified squamous epithelium, is part_of the epithelium of esophagus, and superficial_to the stratum spinosum of esophageal epithelium.
The PR has been created and can be reviewed here: https://github.com/obophenotype/uberon/pull/3540
@dragon-ai-agent
