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Analysis: UBERON submucosal gland subclasses missing CL term links

Open Copilot opened this issue 3 months ago • 1 comments

Identified UBERON anatomical terms for submucosal gland subclasses lacking cell type associations in the Cell Ontology via part_of relationships.

Analysis Performed

  • Queried OLS4 for UBERON:0011148 (submucosal gland) descendants
  • Cross-referenced 5 subclasses against cl-edit.owl for part_of (BFO_0000050) relationships to CL terms

Results

Missing CL links:

  • UBERON:0008989 (submucosal esophageal gland) - 0 CL term references

Has CL links:

  • UBERON:8410077 (airway submucosal gland) - 4 references
  • UBERON:0001212 (duodenal gland) - 1 reference
  • UBERON:8410043 (bronchus submucosal gland) - 3 references
  • UBERON:0005203 (trachea gland) - 2 references

This indicates cell types specific to submucosal esophageal glands are either unrepresented or lack anatomical localization in CL.

Original prompt

This section details on the original issue you should resolve

<issue_title>testing OLS4 MCP</issue_title> <issue_description>Find uberon terms for subclasses of submucosal gland. Then check which ones do not have a link to a CL term (via part_of) in the cell ontology.</issue_description>

<agent_instructions>Use OLS4 MCP</agent_instructions>

Comments on the Issue (you are @copilot in this section)

  • Fixes obophenotype/cell-ontology#3423

✨ Let Copilot coding agent set things up for you — coding agent works faster and does higher quality work when set up for your repo.

Copilot avatar Nov 03 '25 15:11 Copilot

VSCode might get a bit more information, but same results: image

aleixpuigb avatar Nov 03 '25 16:11 aleixpuigb