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new term proposal catecholaminergic neuron

Open GoogleCodeExporter opened this issue 10 years ago • 8 comments


Need term catecholaminergic neuron
Def: Neurons that produce dopamine, norephinephrine or adrenaline.  CA 
synthesis involves four enzymes: tyrosine hydroxylase (TH), aromatic amino acid 
decarboxylase (AADC), dopamine b-hydroxylase (DbH), and 
phenylethanolamine-N-methyl transferase (PNMT) PMID:10191060 ISBN:
9780521442510     

Notes: Frequently used when describing the developing nervous system in 
zebrafish.  Cells express th or th2 genes.  
PMID: 12128258   

Original issue reported on code.google.com by [email protected] on 20 Mar 2014 at 5:54

GoogleCodeExporter avatar Jun 04 '15 18:06 GoogleCodeExporter

Original comment by [email protected] on 2 Dec 2014 at 7:30

GoogleCodeExporter avatar Jun 04 '15 18:06 GoogleCodeExporter

Seems like a valid term. Is this still needed @cerivs?

addiehl avatar Oct 06 '21 19:10 addiehl

Yes please.

cerivs avatar Oct 06 '21 22:10 cerivs

This should be added using the logical definition pattern already in place for other neurons classified by NT.

e.g.

image image

For this we need to request 'catecholamine secretion, neurotransmission' from GO and use that in the logical definition.

dosumis avatar Oct 07 '21 10:10 dosumis

Some comments:

The proposed text def is: "Neurons that produce dopamine, norephinephrine or adrenaline. CA synthesis involves four enzymes: tyrosine hydroxylase (TH), aromatic amino acid decarboxylase (AADC), dopamine b-hydroxylase (DbH), and phenylethanolamine-N-methyl transferase (PNMT)"

  • "Neurons" should be in singular form.

  • The term epinephrine vs adrenaline should be used consistently:

A neuron that produces dopamine, norephinephrine or epinephrine. OR A neuron that produces dopamine, noradrenaline or adrenaline.

  • The gloss may be too broad for the term 'catecholaminergic neuron'.

  • The following GO terms already exist:

GO:0061527 'dopamine secretion, neurotransmission' GO:0061533 'norepinephrine secretion, neurotransmission' GO:0061529 'epinephrine secretion, neurotransmission'

Given that, should a new term 'catecholamine secretion, neurotransmission' be created in GO?

FYI @shawntanzk

ghost avatar Jul 25 '22 12:07 ghost

Ideally having a new term 'catecholamine secretion, neurotransmission' that has all the catecholamine secretion under it would be ideal. I'll create a ticket there. However, if there is any issue, we can also manually assert given its only 3. Give this ticket is from 2015 I don't think there is any rush. Will wait to see what GO says about the new term

shawntanzk avatar Aug 01 '22 08:08 shawntanzk

@bvarner-ebi @shawntanzk, do you think this term can be the same as the one on row 37?

anitacaron avatar Oct 24 '22 19:10 anitacaron

from definition, yes, though my assumption is that the spleen is innervated by catecholaminergic neuron, and not has them? That being said given its a MIRACL sheet, I assume its just for term addition, in which case, yes, that is the same term.

shawntanzk avatar Oct 24 '22 20:10 shawntanzk

Hi @cerivs, thank you for your request. Would you still want to include the following comment in the term?

Frequently used when describing the developing nervous system in zebrafish. Cells express th or th2 genes. (PMID: 12128258)

If so, could you provide your ORCID number to add, please?

aleixpuigb avatar May 18 '23 14:05 aleixpuigb

Hi, Thank you. The note is still applicable. My ORCID is 0000-0002-2244-7917

cerivs avatar May 18 '23 16:05 cerivs

Thank you, @cerivs. This class has been created and will be available in the new released scheduled for today.

aleixpuigb avatar May 22 '23 10:05 aleixpuigb