[NTR] circulating T follicular helper cell

[franasa]

Note - please check that the term does not already exist (check OLS: https://www.ebi.ac.uk/ols/ontologies/cl)

Preferred term label: circulating T follicular helper cell

Synonyms circulating Tfh cell, cTfh cell, blood memory T follicular helper cell

Definition (free text, please give PubMed ID in format PMID:XXXXXX)

CD3+ CD4+ CD45RA- CXCR5+ alpha-beta T cells in the blood comprise the circulating memory compartment of T follicular helper cells. They share functional properties with Tfh cells in the germinal center and have been shown to efficiently induce B cell activation in vitro.

PMID:21215658; PMID:24998903; PMID:25836312

Parent cell type term (check the hierarchy here https://www.ebi.ac.uk/ols/ontologies/cl):

CD4-positive helper T cell

What is the anatomical structure that the cell is a part of? Please check Uberon: https://www.ebi.ac.uk/ols/ontologies/uberon

Blood UBERON:0000178

Your nano-attribution (ORCID)

0000-0001-5286-9013

Any additional notes or concerns

[github-actions[bot]]

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[dosumis]

@addiehl - can you address?

[paolaroncaglia]

@addiehl could you comment, please? This is the last immune-related query for today. Thank you.

[addiehl]

I will work on this after the semester ends in mid-May.