question about "site directed mutagenesis" definition/usage

[sbello]

Second ticket from the Alliance review see #1366 for background

The term "site-directed mutagenesis" (OBI:0002619) is currently defined as "An induced mutation in which a specific base change is programmed into the sequence of a synthetic primer." Several of the Alliance members use this term in a broader sense to mean any mutagenesis method that is directed towards a specific gene(s) or part of a gene. Is the intention for this term to be specific to mutation of synthetic primers? If so would it be possible to alter the label to reflect the narrower meaning of the term? Something like "site-directed mutagenesis of a primer"

In the list of new terms we are working up for submission to OBI we have a broadly defined term currently using the label "directed mutagenesis" that is what most of us would interpret as "site directed mutagenesis" that we plan to propose be the parent term for classes like "targeted mutagenesis" and "endonuclease mediated mutagenesis" and a sibling to "random mutagenesis" (OBI:0002620)

Thanks, Sue

[hectorguzor]

Discussed on OBI call 2021-06-14: agree that label should reflect the textual definition.