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Sex determination Option

Open maxulysse opened this issue 5 years ago • 2 comments

Issue by @apeltzer, moved from SciLifeLab#688

Is your feature request related to a problem? Please describe.

If you don#t know the sex of an individual, one could run simple scripts to perform sex determination. This is commonly done in population genetics and there are quite a bunch of scripts to perform that automatically, more or less checking chrX/chrY ratios with thresholds.

Describe the solution you'd like

Having an optional step may be to run sex determination, as we do have cases where we don't have the information....

maxulysse avatar Jan 27 '20 13:01 maxulysse

It is also very useful as a control when running multiple clinical samples. We can cross the expected sex for the sample with the sex determination done to detect possible errors in sample handling / processing.

egenomics avatar Apr 27 '22 14:04 egenomics

@apeltzer suggested to look at peddy or Sex.DetERRmine which are both already available in MultiQC.

SusiJo avatar Oct 12 '22 09:10 SusiJo