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A stitching platform for InXight
If you filter to principle substances that are antiviral, oseltamivir is NOT included, but it is included if you list all substances. https://drugs.ncats.io/substances?q=(comments:%22Pharmacologic%20Substance%5BC1909%5D%7CAnti-Infective%20Agent%5BC254%5D%7CAntiviral%20Agent%22)%20AND%20(%22oseltamivir%22)&facet=Development%20Status%2FUS%20Approved%20Rx&page=1 https://drugs.ncats.io/substances?q=(comments:%22Pharmacologic%20Substance%5BC1909%5D%7CAnti-Infective%20Agent%5BC254%5D%7CAntiviral%20Agent%22)%20AND%20(%22oseltamivir%22)&facet=Development%20Status%2FUS%20Approved%20Rx&facet=Substance%20Form%2FPrincipal%20Form&page=1 The principle substance for that drug...
2-AMINO-3-HYDROXY-BUTANOIC ACID 760PJT2SS0 is merged with an NPC entry for threonine --- what a mess See also: https://stitcher.ncats.io/api/stitches/v1/2ZD004190S NPC entry should likely be replace with stereo-specific structure to fix?
caodac:hamster: 2:42 PM. June 9, 2020 on the next build we should include chebi
The parent drug should probably be merged with its isotopically-enriched form, if only the latter is marketed. Florbetapir https://drugs.ncats.io/substances?q=%22FLORBETAPIR%20F-18%22&facet=Substance%20Form%2FPrincipal%20Form
We should add a way to test for content during build / pull requests - especially random cases that I come across in conversations. For example: Mifamurtide - approved in...
Subtask for:https://www.wrike.com/open.htm?id=183728532
TODO Summary:approvedYear should use the earliest Marketed date NOT the earliest ApprovalRx date.Drugs@FDA listed drugs that are marked "Discontinued" AND with a Federal Register determination should be marked as Approved...
Use a Supplementary Table 1 from https://www.nature.com/nrd/journal/vaop/ncurrent/full/nrd.2017.194.html#supplementary-information(attached)TODO □ clean up and add UNIIs □ incorporate into stitcher
Calculator Fix -- 'Export Only' Jurisdiction Issue
EUGENOL 3T8H1794QW US Unapproved, Marketed Somewhere Source: Dry Socket https://drugs-dev.ncats.io/ginas/app/drug/3T8H1794QWDigging into its stitcher entry https://stitcher.ncats.io/api/stitches/v1/3T8H1794QWThere are plenty of DailyMed prods to cite, including: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=27f82004-adeb-1112-e054-00144ff8d46c&audience=consumer1. Perhaps prioritize citing DailyMed to other...